- Link to my current CV (Aug 2021)
- Link to my publications on NCBI
- Link to my dissertation on Texas ScholarWorks
Single Cell Epigenomics at the Gene Regulation ObservatoryI only recently moved into this new role, but I'll be updating this space frequently with wet-lab and computational efforts.
Functional Genomics: Cardiovascular GeneticsIn the Ellinor laboratory, I worked on a variety of projects, many of which are now being published! Many of these projects also have results viewable at the Broad Cardiovascular Disease knowledge portal. A selection of publications in which I've been involved include:
- Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis
- Epigenetic maps of chromatin states in healthy human left atrial tissue
- Genetic determinants of P-wave duration (conduction through the atria)
- A very large GWAS for the PR interval (measures conduction through the AV node)
- A massive single nucleus RNA-seq study of the healthy human heart
- Monogenic and polygenic contributions to AF risk
- Pitx2c promoter-enhancer interactions and AF (with Jim Martin's lab)
Functional Genomics: Glioblastoma multiformeIn the Iyer lab, I worked on several projects that relate to the genomics of glioblastoma multiforme (GBM).
The culmination of my work there was to profile histone PTMs and RNA-seq in several primary GBM lesions. I also did collaborations with cardiologists at St. David's Hospital, and with Dr. Richard Aldrich (with whom I did a 3 year stint as a laboratory technician).
- Enhancers and bivalent regions clustered based on molecular subtype
- allele specific bias in ChIP-seq
- eQTL analysis of the GBM genome
- Selective genotyping of individuals undergoing cardiac ablation for atrial fibrillation
- Amino acid conservation across many phyla for the highly conserved calcium signaling protein calmodulin